Submillimeter-Accurate Marker Localization within Low Gradient Magnetic Particle Imaging Tomograms

Florian Griese, Tobias Knopp, René Werner, Alexander Schlaefer, Martin Möddel

Abstract


Magnetic Particle Imaging (MPI) achieves a high temporal resolution, which opens up a wide range of real-time medical applications such as device tracking and navigation. These applications usually rely on automated techniques for finding and localizing devices and fiducial markers in medical images. In this work, we show that submillimeter-accurate automatic marker localization from low gradient MPI tomograms with a spatial resolution of several millimeters is possible. Markers are initially identified within the tomograms by a thresholding-based segmentation algorithm. Subsequently, their positions are accurately determined by calculating the center of mass of the gray values inside the pre-segmented regions. A series of phantom measurements taken at full temporal resolution (46 Hz) is used to analyze statistical and systematical errors and to discuss the performance and stability of the automatic submillimeter-accurate marker localization algorithm.

Keywords


Magnetic Particle Imaging; Image Processing; Marker Localization; Navigation

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Copyright (c) 2017 Florian Griese, Tobias Knopp, René Werner, Alexander Schlaefer, Martin Möddel

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