One-Dimensional Multi-Frequency Spectrometer

Christian Knopke, Bradley W Ficko, Solomon G Diamond

Abstract


Magnetic Particle Spectroscopy (MPS) is an important measurement method to characterize the non-linear behavior of magnetic nanoparticles (MNPs). MPS systems provide valuable data for developing efficient magnetic particle imaging (MPI) methods and optimizing MNP contrast agents. We developed a multiple-excitation-coil spectrometer to recreate AC field patterns that are otherwise only found in 3D MPI systems. The presented Nanoparticle Characterization System (NCS) is capable of creating gradient fields and multi-frequency excitation fields as well as AC field-free-points. With its integrated sample mover, the NCS enables investigations into the effects of these field patterns on samples of > 0.1 µg iron mass in up to 100 µl volume along one dimension.

Int. J. Mag. Part. Imag. 5(1), 2019, Article ID: 1907002, DOI: 10.18416/IJMPI.2019.1907002


Keywords


MPI; Magnetic Particle Imaging; Magnetic Particle Spectroscopy; MPS; SPION; System Design; Field Free Point; FFP; Magnetic Nanoparticles;

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References


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