International Journal on Magnetic Particle Imaging
Vol 6 No 1 (2020): Int J Mag Part Imag
https://doi.org/10.18416/IJMPI.2020.2003004

Research Articles

Investigating Spatial Resolution, Field Sequences and Image Reconstruction Strategies using Hybrid Phantoms in MPI

Main Article Content

Anselm von Gladiss (Institute of Medical Engineering, University of Lübeck), Matthias Graeser (Section for Biomedical Imaging, University Medical Center Hamburg-Eppendorf Institute for Biomedical Imaging, Hamburg University of Technology), Aileen Cordes (Institute of Medical Engineering, University of Lübeck), Anna C. Bakenecker (Institute of Medical Engineering, University of Lübeck), André Behrends (Institute of Medical Engineering, University of Lübeck), Xin Chen (Institute of Medical Engineering, University of Lübeck), Thorsten M. Buzug (Institute of Medical Engineering, University of Lübeck)

Abstract

Hybrid phantoms allow for measurement-based evaluation of particle samples, reconstruction algorithms and field sequences without need of a Magnetic Particle Imaging (MPI) scanning device. Even dynamic hybrid phantoms can be generated using dynamic magnetic offset fields. Multi-dimensional Magnetic Particle Spectrometers are capable of emulating both hybrid system matrices and hybrid phantoms, which can be reconstructed into images. It is shown that a spatial resolution of few hundred micrometres can be achieved for both one- and multi-dimensional excitation using MPI technology. The spatial resolution of reconstructed images increases when including additional receive channels into the reconstruction process. For multi-dimensional imaging the sine-based Lissajous trajectory outperforms the cosine-based Lissajous trajectory in terms of spatial resolution. Both the high signal to noise ratio of a spectrometer and the versatility of hybrid phantom design will enforce innovative measurement-based research on key parameters for MPI.
 
Int. J. Mag. Part. Imag. 6(1), 2020, Article ID: 2003004, DOI: 10.18416/IJMPI.2020.2003004

Article Details

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