HYPER localized hyperthermia – early results

Matthias Weber; Daniel Hensley; Blayne Kettlewell; Andrew Mark; Ryan Orendorff; Maximilian Peters; Brice Tiret; Elaine Yu; Patrick Goodwill

doi:10.18416/IJMPI.2020.2009061

International Journal on Magnetic Particle Imaging IJMPI
Vol. 6 No. 2 Suppl 1 (2020): Int J Mag Part Imag
https://doi.org/10.18416/IJMPI.2020.2009061

Proceedings Articles

HYPER localized hyperthermia – early results

Matthias Weber (Magnetic Insight), Daniel Hensley , Blayne Kettlewell , Andrew Mark , Ryan Orendorff , Maximilian Peters , Brice Tiret , Elaine Yu , Patrick Goodwill

Abstract

In magnetic fluid hyperthermia (MFH), Magnetic Nanoparticles (MNPs) dissipate heat when exposed to alternating magnetic fields (AMF). MFH is used for targeted energy deposition for targeted drug-delivery or cancer therapy. To avoid heat deposition in all areas with high particle concentration, a gradient field featuring a field-free area (FFR) can be utilized to isolate heating a target region. In this work, we present preliminary results with a localized hyperthermia system, HYPER, that features a mechanically actuated gradient that enables adjusting the heating region’s size and position. The size of the heating region in our prototype is verified by measuring the full width at half maximum (FWHM) of the specific absorption rate (SAR) point spread function (PSF) and compared to a theoretical heating model.

Int. J. Mag. Part. Imag. 6(2), Suppl. 1, 2020, Article ID: 2009061, DOI: 10.18416/IJMPI.2020.2009061

Most read articles by the same author(s)

Matthias Weber, Jonas Beuke, Anselm von Gladiss, Ksenija Gräfe, Patrick Vogel, Volker C. Behr, Thorsten M. Buzug, Novel Field Geometry Using Two Halbach Cylinders for FFL-MPI , International Journal on Magnetic Particle Imaging IJMPI: Vol. 4 No. 2 (2018)
Benedikt Mues, Brice Tiret, Benedict Bauer, Jeanette Ortega, Thomas Gries, Thomas Schmitz-Rode, Patrick Goodwill, Ioana Slabu, MPI visualization and inductive heating of hybrid implant fibers , International Journal on Magnetic Particle Imaging IJMPI: Vol. 6 No. 2 Suppl 1 (2020)
Olivia C. Sehl, Brice Tiret, Maryam A. Berih, Ashley V. Makela, Patrick W. Goodwill, Paula J. Foster, MPI region of interest (ROI) analysis and quantification of iron in different volumes , International Journal on Magnetic Particle Imaging IJMPI: Vol. 8 No. 1 (2022)
Marco Gerosa, Gang Ren, Yanrong Zhang, Patrick Goodwill, Jim Mansfield, Pasquina Marzola, Max Wintermark, Preliminary results: Imaging of in situ labeled Tumor-Associated Macrophages with Magnetic Particle Imaging , International Journal on Magnetic Particle Imaging IJMPI: Vol. 6 No. 2 Suppl 1 (2020)
Federica Vurro, Marco Gerosa, Alice Busato, Matilde Muccilli, Emil Milan, Jeff Gaudet, James Mansfield, Patrick Goodwill, Enrico Forlin, Filippo Gherlinzoni, Gianni Morana, Michele Gottardi, Paolo Matteazzi, Max Wintermark, Adolfo Speghini, Pasquina Marzola, An iron-oxide nanoparticle with therapeutic capability in Magnetic Fluid Hyperthermia and diagnostic capability in MRI and MPI , International Journal on Magnetic Particle Imaging IJMPI: Vol. 8 No. 1 Suppl 1 (2022)
Harald Radermacher, Franziska Schrank, Dennis Pantke, Florian Mueller, Maximilian Peters, Volkmar Schulz, Highly flexible gradiometer coil arrangement offering improved passive compensation for multi-frequency MPI , International Journal on Magnetic Particle Imaging IJMPI: Vol. 9 No. 1 Suppl 1 (2023)
Olivia Sehl, Brice Tiret, Maryam Berih, Ashley Makela, Patrick Goodwill, Paula Foster, MPI region of interest (ROI) analysis and quantification of iron in different volumes , International Journal on Magnetic Particle Imaging IJMPI: Vol. 8 No. 1 Suppl 1 (2022)
Ali Shakeri-Zadeh, Mollie O'Brien, Alexandra Johns, Brice Tiret, Adnan Bibic, Nicholas Maragakis, Geoffrey Cotin, Benjamin Ayela, Delphine Felder-Flesch, Jeff W. M. Bulte, MPI of SuperSPIO20-labeled ALS patient-derived, genome-edited iPSCs and iPSC-derived motor neurons , International Journal on Magnetic Particle Imaging IJMPI: Vol. 8 No. 1 Suppl 1 (2022)
Toby Sanders, Erica Mason, Justin Konkle, Patrick Goodwill, Multi-harmonic Gridded 3D Deconvolution (MH3D) for Image Reconstruction in MPI , International Journal on Magnetic Particle Imaging IJMPI: Vol. 10 No. 1 Suppl 1 (2024)
Toby Sanders, Justin Konkle, Patrick Goodwill, Modeling the Image Reconstruction Problem in MPI , International Journal on Magnetic Particle Imaging IJMPI: Vol. 9 No. 1 Suppl 1 (2023)

1 2 > >>

International Journal on Magnetic Particle Imaging IJMPI

Main Article Content

Abstract

Article Details

Most read articles by the same author(s)