International Journal on Magnetic Particle Imaging
Vol 6 No 2 Suppl. 1 (2020)

Proceedings Articles

Development of a microfluidic platform for the synthesis of MPI tracer materials

Main Article Content

David Heinke (nanoPET Pharma GmbH), Alexander Kraupner , Jörg Schemberg , Stefan Wiedemeier , Andreas Briel 


To avoid the disadvantages of classical batch-wise coprecipitation in the synthesis of iron oxide nanoparticles we developed a microfluidic synthesis platform with continuous flow mode which enables a faster and more efficient adjustment of relevant parameters like pH-value, temperature and educt concentration. Initial results of the electrostatically stabilized particles demonstrate the high potential for the use as tracer in magnetic particle imaging or contrast agent in magnetic resonance imaging outperforming the efficacy of the current gold-standard Resovist®.
Int. J. Mag. Part. Imag. 6(2), Suppl. 1, 2020, Article ID: 2009007, DOI: 10.18416/IJMPI.2020.2009007

Article Details