Simultaneous magnetic particle imaging (MPI) and temperature mapping using multi-color MPI

Abstract

Magnetic Particle Imaging (MPI) is a novel imaging technique based on the non-linear magnetization response of super-paramagnetic iron oxide nanoparticles (SPIOs). It has previously been shown that beside the spatial particle distribution, information about the particle type, its environment, and the particle temperature can be obtained from the magnetic particle signal. Successful separation of particle types and temperature measurements have been reported in spectroscopic experiments, but a simultaneous mapping of the particle distribution and temperature in a spatially encoded imaging experiment has not been performed. This work presents simultaneous imaging and temperature mapping using a ‘multi-color’ reconstruction approach.