Displacement measurement of magnetic particles by ultrasonic vibration

Abstract

Signal detection methods of conventional magnetic particle imaging (MPI) require large coils and multiple power supplies for detecting signals from magnetic nanoparticles (MNPs). In connection to this, there is a concern about the safety of the living body. Therefore, a new signal detection method based on the vibration of MNPs has been proposed in this study. Further, to establish this method using ultrasonic vibration, the displacement of the MNPs by a focused ultrasonic transducer has been evaluated using experiment and the finite element method. Iron oxide particles have been used instead of MNPs to investigate whether ultrasonic waves can be used for generating vibrations in a simulated biological object. From the experimental results, the displacement of the iron oxide particles in agar has been observed to be approximately 51.8 ?m, which is different from the simulation results, indicating that the finite element model requires improvement to match the experimental conditions.