Main Article Content
This work is licensed under a Creative Commons Attribution 4.0 International License.
X-space is a rapid reconstruction technique based on time domain signals for magnetic particle imaging (MPI). However, due to particle relaxation effect, signal distortion and image blur will inevitably occur in high drive field and low gradient field. In this work, we propose a hybrid harmonic projection (HHP) reconstruction method based on time-frequency spectrum, which uses the response harmonic amplitude in a short time for continuous projection reconstruction. In order to more accurately simulate the actual dynamic magnetic field distribution, a 3D finite element model of MPI scanner was constructed. Simulation and reconstruction results show that harmonic projection has the advantage of realizing high resolution in high drive field compared with time domain projection. In addition, HHP can significantly reduce the high order harmonic artifacts and show good quantitative imaging performance.