International Journal on Magnetic Particle Imaging
Vol 8 No 1 Suppl 1 (2022): Int J Mag Part Imag
https://doi.org/10.18416/IJMPI.2022.2203054

Proceedings Articles

Response characteristics of magnetic particle spectroscopy under different excitation waveforms

Main Article Content

Bo Zhang  , Haoran Zhang , Yanjun Liu , Jie He , Jing Zhong , Hui Hui  , Jie Tian  

Abstract

Magnetic particle spectroscopy (MPS) is a method to characterize the characteristics of magnetic nanoparticles (MNP), which is of great significance for the research of magnetic particle imaging (MPI) and magnetic hyperthermia. In the MPS system, the waveform characteristics of the excitation magnetic field will directly impact the received particle signal. Aiming at the problem that sinusoidal wave is used by default in most current studies, this study has studied the excitation effect of the trapezoidal wave and triangular wave. The results show that under the excitation frequencies of 10kHz and 15kHz, the excitation effect of the trapezoidal wave is obviously better than the other two waveforms, and the effect of the triangular wave is the worst. The research is enormously significant to the optimization of MPS and even MPI.

Article Details

References

[1] B. Gleich, Tomographic imaging using the nonlinear response of magnetic particles, Nature, vol. 435, pp. 1214–1217, Jun. 2005.
[2] P. Chandrasekharan , A perspective on a rapid and radiationfree tracer imaging modality, magnetic particle imaging, with promise for clinical translation, Brit. J. Radiol., vol. 91, pp. 1091, Nov. 2018.
[3] T. Knopp, Magnetic particle imaging: From proof of principle to preclinical applications, Phys. Med. Biol., vol. 62, pp. 124–178, Jun. 2017.
[4] K. Wu, Magnetic particle spectroscopy-based bioassays: methods, applications, advances, and future opportunities, Journal of Physics D-Applied Physics, vol.52, pp. 173001, Apr. 2019.
[5] Z. W. Tai, A High-Throughput, Arbitrary-Waveform, MPI Spectrometer and Relaxometer for Comprehensive Magnetic Particle Optimization and Characterization, Scientific Reports, vol.6, pp. 34180, Sep. 2016.
[6] C. Top, An arbitrary waveform magnetic nanoparticle relaxometer with an asymmetrical three-section gradiometric receive coil, Turkish Journal of Electrical Engineering and Computer Sciences, vol. 28, pp.1344-1354, May. 2020.
[7] A. M. Rauwerdink , Nanoparticle temperature estimation in combined ac and dc magnetic fields, Phys. Med. Biol. vol.54, pp. L51-5, Oct. 2009.
[8] K. Wu, In vitro viscosity measurement on superparamagnetic nanoparticle suspensions, IEEE Trans. Magn. , vol. 52, pp. 1–4, July. 2016.