International Journal on Magnetic Particle Imaging IJMPI
Vol 8 No 1 Suppl 1 (2022): Int J Mag Part Imag
High gradient nested Halbach system for steering magnetic particles
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To transport drugs within the brain to their desired application site it is necessary to overcome the bloodbrain barrier (BBB). To protect the brain from the penetration of harmful substances, the BBB forms anendogenous protection. Different approaches exist to overcome the BBB. One possible approach are magnetic nanoparticles which can be used to move drugs through the blood-brain barrier using magnetic guidance. The system described here consists of three rings of permanent magnets in Halbach configuration with an inner diameter of 5.5 cm, which generate a high gradient of 5.8 T/m at the center, which can be used to study and optimize magnetic transport systems on cell models of a BBB.