International Journal on Magnetic Particle Imaging
Vol 8 No 1 Suppl 1 (2022): Int J Mag Part Imag
https://doi.org/10.18416/IJMPI.2022.2203045

Proceedings Articles

MPI visualization of hybrid implant fibers using different system matrices

Main Article Content

Benedikt Mues (Applied Medical Engineering, Helmholtz Institute, Medical Faculty, RWTH Aachen University, Germany), Max Schoenen  (Applied Medical Engineering, Helmholtz Institute, Medical Faculty, RWTH Aachen University, Germany), Benedict Bauer  (Institut für Textiltechnik, RWTH Aachen University, Germany), Gries Thomas (Institut für Textiltechnik, RWTH Aachen University, Germany), Dennis Pantke  (Institute for Experimental Molecular Imaging, Helmholtz Institute, RWTH Aachen University, Germany), Volkmar Schulz  (Institute for Experimental Molecular Imaging, Helmholtz Institute, RWTH Aachen University, Germany), Thomas Schmitz-Rode  (Applied Medical Engineering, Helmholtz Institute, Medical Faculty, RWTH Aachen University, Germany), Ioana Slabu  (Applied Medical Engineering, Helmholtz Institute, Medical Faculty, RWTH Aachen University, Germany)

Abstract

Hybrid stents can be used in cardiovascular applications and in hollow organ tumor therapy. They open the occluded area and can induce local hyperthermia by application of an alternating magnetic field (AMF) destroying cancer cells. Here, we investigate hybrid fibers made of polypropylene (PP) fibers with incorporated magnetic nanoparticles (MNP) via magnetic particle imaging (MPI). An influence of the MNP mobility and MNP agglomeration state as well as the orientation of elongated MNP agglomerations with respect to the drive field of the system matrix reference on the image reconstruction were determined. Best image resolution for a phantom consisting of two parallel fibers was achieved with reconstructions using system matrices of a fiber where MNP agglomerations point in the same direction as the ones of the phantom with respect to the drive field. Changes in MNP mobility, agglomeration state and their preferred directions have effects on the resulting image quality and must be considered in future measurements of complex structures of hybrid fibers.

Article Details

References

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