Human-Sized Lightweight Head-Scanner Design

Abstract

Brain imaging includes various techniques for direct or indirect imaging of the structure or function of the brain. Established clinical imaging techniques such as computed tomography (CT) and magnetic resonance imaging (MRI) require the referral of patients to specialized centres with stationary brain scanners in a shielded environment. However, these restrictions limit the accessibility for many people. For example, it may be difficult to assess time-critical neurological emergencies in a preclinical setting, or to monitor brain function of patients in intensive care units. Here we demonstrate the concept for a wearable brain scanner based on the magnetic particle spectroscopy technology with superparamagnetic iron-oxide nanoparticles (SPIONs) as contrast agent.