International Journal on Magnetic Particle Imaging
Vol 8 No 1 Suppl 1 (2022): Int J Mag Part Imag
https://doi.org/10.18416/IJMPI.2022.2203002

Proceedings Articles

A microrobot for endovascular aneurysm treatment steered and visualized with MPI

Main Article Content

Anna C. Bakenecker (Fraunhofer Research Institution for Individualized and Cell-Based Medical Engineering IMTE, Lübeck, Germany), Anselm von Gladiss  (Institute of Medical Engineering, University of Lübeck, Ratzeburger Allee 160, 23562 Lübeck, Germany), Hannes Schwenke  (Department of Neuroradiology, University Hospital Schleswig-Holstein, Campus Lübeck, Ratzeburger Allee 160, 23562 Lübeck, Germany), André Behrends (Fraunhofer Research Institution for Individualized and Cell-Based Medical Engineering IMTE, Lübeck, Germany), Thomas Friedrich  (Fraunhofer Research Institution for Individualized and Cell-Based Medical Engineering IMTE, Lübeck, Germany), Kerstin Lüdtke-Buzug  (Institute of Medical Engineering, University of Lübeck, Ratzeburger Allee 160, 23562 Lübeck, Germany), Alexander Neumann  (Institute of Medical Engineering, University of Lübeck, Ratzeburger Allee 160, 23562 Lübeck, Germany), Joerg Barkhausen  (Department of Radiology and Nuclear Medicine, University of Lübeck, Ratzeburger Allee 160, 23562 Lübeck, Germany), Franz Wegner  (Department of Radiology and Nuclear Medicine, University of Lübeck, Ratzeburger Allee 160, 23562 Lübeck, Germany), Thorsten Buzug (Institute of Medical Engineering, University of Lübeck, Ratzeburger Allee 160, 23562 Lübeck, Germany)

Abstract

The steering of microrobots by using magnetic fields offers applications for minimally invasive surgery or for establishing drug delivery scenarios. On the one hand, magnetic particle imaging (MPI) offers a tomographic, real-time visualization of the used magnetic microrobots. On the other hand, an MPI scanner can apply magnetic fields, which a microrobot can be steered with. Hence, MPI is of great interest for realizing the tracking and navigation of microrobots. Here, we show that a microrobot, which has been coated with superparamagnetic iron oxide nanoparticles (SPIONs) can be steered through a patient specific phantom of the middle cerebral artery into an aneurysm, where it should occlude the aneurysm and can be potentially used for a triggered drug release or a hyperthermia treatment. The acquired MPI images show that a tracking accuracy of 0.68 mm is achieved.   

Article Details