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4D flow experiments, as known from MRI, are useful to examine the fluid dynamics in complex vessel geometries with high accuracy. The transfer to a positive contrasted fast and sensitive modality, such as MPI, offers new insights into dynamic particle flow under real-time visualization. In particular, measurements in 3D printed vascular phantoms are beneficial since they allow studies of the complicated flow-related interrelations causing the development of pathologies and also provide a quality control for the development of more realistic vascular phantoms. The presented framework provides an easy-to-use processing from extraction of desired vessel structures from 3D MRI or CT data over preparation them for 3D printing and further processing to final measurements.