International Journal on Magnetic Particle Imaging IJMPI
Vol. 8 No. 1 Suppl 1 (2022): Int J Mag Part Imag
https://doi.org/10.18416/IJMPI.2022.2203023

Proceedings Articles

Side Lobe Informed Center Extraction (SLICE): a projection-space forward model reconstruction for a 2D imaging system

Main Article Content

Erica Ellis Mason (MGH-HST A.A. Martinos Center for Biomedical Imaging, Harvard-MIT Health Sciences & Technology), Stephen F. Cauley (Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, USA), Eli Mattingly (Massachusetts Institute of Technology, Cambridge, MA, USA), Monika Sliwiak (Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, USA), Lawrence L. Wald (Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, USA)

Copyright (c) 2022 Erica Ellis Mason, Stephen F. Cauley, Eli Mattingly, Monika Sliwiak, Lawrence L. Wald

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Abstract

A two-dimensional MPI acquisition allows signal from SPIONs outside the intended 2D imaging plane to interfere destructively with that from SPIONs in the desired slice, creating unwanted artifacts in the reconstructed image. We address this "side-lobe" signal interference with a Side Lobe Informed Center Extraction (SLICE) reconstruction, which utilizes a projection-space 3D forward model of the detected harmonics. The developed method reduces the out-of-plane interference artifacts in the 2D image reconstruction without the need to change the simplified acquisition schemes or hardware of the gradiometer detection based FFL system, for example by adding true 3D encoding which would interfere with the goal of fast <5 sec temporal resolution needed for functional brain imaging.

Article Details

References

1] E. Mattingly, E. E. Mason, K. Herb, M. Sliwiak, K. Brandt, C. Z. ´Cooley, and L. L. Wald. OS-MPI: An open-source magnetic particle imaging project. Int. J. Magn. Part. Imaging, 6(2):1–3, 2020,
doi:10.18416/IJMPI.2020.2009059.
[2] P. W. Goodwill, J. J. Konkle, B. Zheng, E. U. Saritas, and S. M. Conolly. Projection x-space magnetic particle imaging. IEEE Trans. Med. Imaging, 31(5):1076–1085, 2012.
[3] J. Weizenecker, B. Gleich, J. Rahmer, H. Dahnke, and J. Borgert. Three-dimensional real-time in vivo magnetic particle imaging. Phys. Med. Biol., 54:L1–L10, 2009, doi:10.1088/0031-
9155/54/5/L01.
[4] D. C. Meeker, Finite Element Method Magnetics, Version 4.2 (21Apr2019 Build), [Online]. Available: https://www.femm.info.
[5] E. E. Mason, C. Z. Cooley, S. F. Cauley, M. A. Griswold, S. M. Conolly, and L. L. Wald. Design analysis of an mpi human functional brain scanner. Int. J. Magn. Part. Imaging, 3(1), 2017,
doi:10.18416/ijmpi.2017.1703008.
[6] P. Goodwill and S. Conolly. Multidimensional x-space magnetic particle imaging. IEEE Trans. Med. Imaging, 30(9):1581–1590, 2011.

Most read articles by the same author(s)

<< < 1 2