International Journal on Magnetic Particle Imaging IJMPI
Vol. 9 No. 1 Suppl 1 (2023): Int J Mag Part Imag

Short Abstracts

Towards simultaneous imaging of temperature and concentration with single-harmonic-based narrowband MPI

Main Article Content

Klaas-Julian Janssen (TU Braunschweig), Jing Zhong (School of Instrumentation and Optoelectronic Engineering, Beihang University, Beijing, China), Thilo Viereck (1 Institut für Elektrische Messtechnik und Grundlagen der Elektrotechnik und LENA, TU Braunschweig, Braunschweig, Germany), Meinhard Schilling (1 Institut für Elektrische Messtechnik und Grundlagen der Elektrotechnik und LENA, TU Braunschweig, Braunschweig, Germany), Frank Ludwig (1 Institut für Elektrische Messtechnik und Grundlagen der Elektrotechnik und LENA, TU Braunschweig, Braunschweig, Germany)

Abstract

Magnetic Particle Imaging (MPI) is a promising imaging modality for medical applications, which exploits the non-linear magnetization curve of magnetic nanoparticles to visualize the spatial distribution of the tracers. In addition to this diagnostic application, MPI can also be used for therapeutic purposes, like magnetic hyperthermia or targeted drug delivery. Both applications require the knowledge of the temperature of the MNPs and their environment. One opportunity to determine the temperature of MNPs is to detect the phase lag of the particles due to the temperature change. With our single-harmonic-based narrowband MPI system we can measure images of the MNP concentration via the harmonic amplitudes and images of the temperature exploiting the phase of a harmonic. As a next step we work on a combination of both modalities to enable a simultaneous and quantitative concentration and temperature imaging.

Article Details

References

[1] B. Gleich, J. Weizenecker, Tomographic imaging using the nonlinear response of magnetic particles, Nature 435 (2005) 1214 – 1217.
[2] J.B. Weaver, A.M. Rauwerdink, E.W. Hansen, Magnetic nanoparticle temperature estimation, Med. Phys. 2009 (1822) 36.
[3] M. Zhou, J. Zhong, W. Liu, Z. Du, Z. Huang, M. Yang, P.C. Morais, Study of magnetic nanoparticle spectrum for magnetic nanothermometry, IEEE Trans. Magn. 51 (2015) 1 – 6.
[4] L. He, W. Liu, Q. Xie, S. Pi, P. Morais, A fast and remote magnetonanothermometry for a liquid environment, Meas. Sci. Technol. 27 (2015), 025901.
[5] J. Wells, H. Paysen, O. Kosch, Temperature dependence in magnetic particle imaging, AIP Adv. 8 (2018).
[6] E. Garaio, J.-M. Collantes, J.A. Garcia, F. Plazaola, O. Sandre, Harmonic phases of the nanoparticle magnetization: an intrinsic temperature probe, Appl. Phys. Lett. 107 (2015), 123103.
[7] J, Zhong, M, Schilling, F, Ludwig, Magnetic nanoparticle temperature imaging with a scanning magnetic particle spectrometer, Meas. Sci. Technol., 2018
[8] C. Stehning, B. Gleich, J. Rahmer, Simultaneous magnetic particle imaging (MPI) and temperature mapping using multi-color MPI, Int. J. Mag. Particle Imaging, Vol 2, No 2, Article ID 1612001.
[9] K.-J. Janssen, M. Schilling, F. Ludwig, J. Zhong, Single harmonic-based narrowband magnetic particle imaging, Meas. Sci. Technol. 33 (2022), 095405.
[10] K. Janssen, J. Zhong, T. Viereck, M. Schilling, F. Ludwig, Quantitative temperature visualization with single harmonic-based magnetic particle imaging, JMMM, Vol 563

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