International Journal on Magnetic Particle Imaging IJMPI
Vol. 10 No. 1 Suppl 1 (2024): Int J Mag Part Imag
https://doi.org/10.18416/IJMPI.2024.2403041

Proceedings Articles

Simulation of a single-sided MPI handheld device with offset magnetic field for spatial encoding

Main Article Content

Qibin Wang (School of Life Science and Technology), Zhonghao Zhang , Lei Li , Franziska Schrank , Harald Radermacher , Volkmar Schulz , Shouping Zhu 

Abstract

Single-sided MPI devices provide images from regions outside of an enclosed scanner but they are constrained by limited in detection depth and non-uniform magnetic field distribution, which restrict imaging quality and sensitivity. In this study, we propose a novel handheld single-sided MPI device that utilizes an offset magnetic field with varying amplitude, coupled with high-frequency dynamic magnetic fields, to excite magnetic nanoparticles and sensitively capture the harmonic variations in spatial distribution. By moving the device horizontally in a direction perpendicular to the depth, two-dimensional spatial distribution information of magnetic nanoparticles can be acquired without the need for classical static selection fields. When the depth distance is 0-15 mm, the best spatial resolution is 1 mm. This technology holds the promise of achieving real-time imaging of superficial human tissue layers with lower cost and a simpler device structure.

Article Details

References

[1] McDonough C, Pagan J, Tonyushkin A. Implementation of the surface gradiometer receive coils for the improved detection limit and sensitivity in the single-sided MPI scanner[J]. Physics in Medicine & Biology, 2022, 67(24): 245009.
[2] Gräfe K, von Gladiss A, Bringout G, et al. 2D images recorded with a single-sided magnetic particle imaging scanner[J]. IEEE transactions on medical imaging, 2015, 35(4): 1056-1065.
[3] Vogel P, Rückert M A, Friedrich B, et al. Critical Offset Magnetic PArticle SpectroScopy for rapid and highly sensitive medical point-of-care diagnostics[J]. Nature Communications, 2022, 13(1): 7230.
[4] Rahmer J, Weizenecker J, Gleich B, et al. Signal encoding in magnetic particle imaging: properties of the system function[J]. BMC medical imaging, 2009, 9: 1-21.

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