International Journal on Magnetic Particle Imaging IJMPI
Vol. 11 No. 1 Suppl 1 (2025): Int J Mag Part Imag

Short Abstracts

Advancing clinical MPI: safety assessment of medical implants in a human cadaver model

Main Article Content

Franz Wegner (Institute of Interventional Radiology, University Hospital Schleswig-Holstein), Thomas Friedrich (Fraunhofer IMTE, Fraunhofer Research Institution for Individualized and Cell-Based Medical Engineering IMTE), Patrick Elfers (Institute of Radiology and Nuclear Medicine, University Hospital Schleswig-Holstein), Florian Kleefeldt (Institute of Anatomy and Cell Biology, University of Würzburg), Dominik Peter (5Department of General, Visceral, Transplant, Vascular and Pediatric Surgery, Center of Operative Medicine, University Hospital Würzburg), Philipp Gruschwitz (Department of Diagnostic and Interventional Radiology, University Hospital Würzburg), Teresa Reichl (Department of Experimental Physics 5 (Biophysics), Julius-Maximilians-University Würzburg), Johanna Günther (Department of Experimental Physics 5 (Biophysics), Julius-Maximilians-University Würzburg), Martin Rückert (Department of Experimental Physics 5 (Biophysics), Julius-Maximilians-University Würzburg), Thomas Kampf (Department of Experimental Physics 5 (Biophysics), Julius-Maximilians-University Würzburg), Volker Behr (Department of Experimental Physics 5 (Biophysics), Julius-Maximilians-University Würzburg), Thorsten Buzug (Fraunhofer IMTE, Fraunhofer Research Institution for Individualized and Cell-Based Medical Engineering IMTE), Roman Kloeckner (Institute of Interventional Radiology, University Hospital Schleswig-Holstein), Jörg Barkhausen (Institute of Radiology and Nuclear Medicine, University Hospital Schleswig-Holstein), Thorsten Bley (Department of Diagnostic and Interventional Radiology, University Hospital Würzburg), Patrick Vogel (Department of Experimental Physics 5 (Biophysics), Julius-Maximilians-University Würzburg), Viktor Hartung (Department of Diagnostic and Interventional Radiology, University Hospital Würzburg)

Abstract

Magnetic Particle Imaging (MPI) is a 3D imaging technology that offers high temporal resolution without ionizing radiation, making it ideal for cardiovascular imaging and the real-time visualization of endovascular interventions. A key safety concern is the potential heating of metallic implants during MPI scans. This study evaluated the thermal behavior of various commercially available medical implants in a perfused human cadaver model. The measurements showed no detectable heating of the tested endovascular devices. A temperature increase of 0.04 K was observed in the tested femoral gamma nail. The study concludes that some commercial medical implants do not heat significantly in the used MPI scanner-setup under realistic conditions, indicating their safety for clinical use.

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