International Journal on Magnetic Particle Imaging IJMPI
Vol. 11 No. 1 Suppl 1 (2025): Int J Mag Part Imag

Short Abstracts

Towards SPION-Enhanced Real-Time Visualization of Onyx Embolization

Main Article Content

Fabio Roeper (Institute for Interventional Radiology, University of Luebeck), Mandy Ahlborg (Fraunhofer IMTE, Fraunhofer Research Institution for Individualized and Cell-based Medical Engineering IMTE, Luebeck, Germany), Thomas Friedrich (Fraunhofer IMTE, Fraunhofer Research Institution for Individualized and Cell-based Medical Engineering IMTE, Luebeck, Germany), Ankit Malhotra (Fraunhofer IMTE, Fraunhofer Research Institution for Individualized and Cell-based Medical Engineering IMTE, Luebeck, Germany), Justin Ackers (Fraunhofer IMTE, Fraunhofer Research Institution for Individualized and Cell-based Medical Engineering IMTE, Luebeck, Germany), Jörg Barkhausen (Institute of Radiology and Nuclear Medicine, University of Luebeck, Luebeck, Germany), Roman Klöckner (Institute for Interventional Radiology, University of Luebeck, Luebeck, Germany), Thorsten M. Buzug (1) Fraunhofer IMTE, Fraunhofer Research Institution for Individualized and Cell-based Medical Engineering IMTE, Luebeck, Germany; 2) Institute of Medical Engineering, University of Luebeck, Luebeck, Germany), Kerstin Lüdtke-Buzug (1) Fraunhofer IMTE, Fraunhofer Research Institution for Individualized and Cell-based Medical Engineering IMTE, Luebeck, Germany; 2) Institute of Medical Engineering, University of Luebeck, Luebeck, Germany), Franz Wegner (1) Institute for Interventional Radiology, University of Luebeck, Luebeck, Germany; 2) Fraunhofer IMTE, Fraunhofer Research Institution for Individualized and Cell-based Medical Engineering IMTE, Luebeck, Germany)

Copyright (c) 2025 Fabio Roeper, Mandy Ahlborg, Thomas Friedrich, Ankit Malhotra, Justin Ackers, Jörg Barkhausen, Roman Klöckner, Thorsten M. Buzug, Kerstin Lüdtke-Buzug, Franz Wegner

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Abstract

Magnetic particle imaging (MPI) is emerging as a promising technique for various clinical applications, including real-time monitoring of endovascular interventions. The use of liquid embolic agents is established for the therapy of vascular pathologies, e.g. malformations. To identify the timepoint of complete hardening is essential for the safe and effective use of such liquid embolization materials. In this study, we aimed to monitor the solidification process of the liquid embolic agent Onyx-20 by integration of superparamagnetic iron oxide nanoparticles (SPIONs). Our findings suggest that the observed differences in the magnetic signal throughout the solidification process are particularly advantageous for the application of multi-contrast MPI techniques, potentially enhancing the monitoring of embolization procedures.

Article Details

References

[1] J. Weizenecker, B. Gleich, J. Rahmer, H. Dahnke, and J. Borgert, “Three-dimensional real-time in vivo magnetic particle imaging,” Phys. Med. Biol., vol. 54, no. 5, p. L1, Feb. 2009, doi: 10.1088/0031-9155/54/5/L01.

[2] M. Utkur, Y. Muslu, and E. U. Saritas, “Relaxation-based viscosity mapping for magnetic particle imaging,” Phys. Med. Biol., vol. 62, no. 9, pp. 3422–3439, Apr. 2017, doi: 10.1088/1361-6560/62/9/3422.

[3] J. Rahmer, A. Halkola, B. Gleich, I. Schmale, and J. Borgert, “First experimental evidence of the feasibility of multi-color magnetic particle imaging,” Phys. Med. Biol., vol. 60, no. 5, p. 1775, Feb. 2015, doi: 10.1088/0031-9155/60/5/1775.

[4] Y. Jiang et al., “Liquid embolic agents for interventional embolization,” ChemPhysMater, vol. 1, no. 1, pp. 39–50, Jan. 2022, doi: 10.1016/j.chphma.2021.09.008.

[5] S. Biederer et al., “Magnetization response spectroscopy of superparamagnetic nanoparticles for magnetic particle imaging,” J. Phys. D: Appl. Phys., vol. 42, no. 20, p. 205007, Sep. 2009, doi: 10.1088/0022-3727/42/20/205007.

[6] S. Draack, M. Schilling, and T. Viereck, “Magnetic particle imaging of particle dynamics in complex matrix systems,” Physical Sciences Reviews, vol. 8, no. 2, pp. 213–237, Feb. 2023, doi: 10.1515/psr-2019-0123.

[7] Y. Muslu, M. Utkur, O. B. Demirel, and E. U. Saritas, “Calibration-Free Relaxation-Based Multi-Color Magnetic Particle Imaging,” IEEE Transactions on Medical Imaging, vol. 37, no. 8, pp. 1920–1931, Aug. 2018, doi: 10.1109/TMI.2018.2818261.

[8] M. Gräser et al., “„Magnetic particle imaging“,” Radiologie, vol. 62, no. 6, pp. 496–503, Jun. 2022, doi: 10.1007/s00117-022-01011-9.

Most read articles by the same author(s)

<< < 2 3 4 5 6 7 8 9 > >>