International Journal on Magnetic Particle Imaging IJMPI
Vol. 11 No. 1 Suppl 1 (2025): Int J Mag Part Imag
https://doi.org/10.18416/IJMPI.2025.2503027

Proceedings Articles

Extending tuning coil loading for improved passive compensation in multi-frequency MPI towards nominal field strength operation

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Harald Radermacher (1) Institute of Imaging and Computer Vision, RWTH Aachen University, Aachen, Germany; 2) Institute for Experimental Molecular Imaging, RWTH Aachen University, Aachen, Germany), Franziska Schrank (1) Institute of Imaging and Computer Vision, RWTH Aachen University, Aachen, Germany; 2) Institute for Experimental Molecular Imaging, RWTH Aachen University, Aachen, Germany), Dennis Pantke (Institute for Experimental Molecular Imaging, RWTH Aachen University, Aachen, Germany), Florian Müller (Institute for Experimental Molecular Imaging, RWTH Aachen University, Aachen, Germany), Volkmar Schulz (1) Institute of Imaging and Computer Vision, RWTH Aachen University, Aachen, Germany; 2) Institute for Experimental Molecular Imaging, RWTH Aachen University, Aachen, Germany; 3) Fraunhofer Institute for Digital Medicine MEVIS, Aachen, Germany)

Copyright (c) 2025 Harald Radermacher, Franziska Schrank, Dennis Pantke, Florian Müller, Volkmar Schulz

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This work is licensed under a Creative Commons Attribution 4.0 International License.

Abstract

In Magnetic Particle Imaging (MPI), minimizing the feedthrough of the excitation signal into the receive signal helps in capturing the fundamental frequency response of the superparamagnetic iron oxide nanoparticle (SPIONs), improving the signal to noise ratio and assisting quantitative measurements. The concept of tuning coils can improve the performance of gradiometer receive coils by inducing suitable signals into the receive coils to reduce the remaining excitation signal without hampering the reception of the particle signal. Adjusting the current in the tuning coils is done by applying loading, controlled via solid state switches. In this work, an arrangement capable for operation at nominal field strength of a multi-frequency MPI (mf-MPI) scanner for mouse sized objects is presented. A high voltage loading board is applied. The adjustment of the load is integrated into an automated control loop.

Article Details

References

[1] Gleich, B. and J. Weizenecker (2005). “Tomographic imaging using the nonlinearresponse of magnetic particles”. In: Nature 435, pp. 1214–1217.
[2] H. Radermacher, F. Schrank, D. Pantke, F. Mueller, M. Peters, and V. Schulz, “Highly flexible gradiometer coil arrangement offering improved passive compensation for multi-frequency MPI,” International Journal on Magnetic Particle Imaging IJMPI, Vol 9 No 1 Suppl 1 (2023), doi:10.18416/IJMPI.2023.2303030.
[3] H. Radermacher, F. Schrank, D. Pantke, F. Mueller, and V. Schulz (2024). “Automated tuning coil loading for improved passive compensation for multi-frequency MPI”. In: Proc. of EMIM.
[4] D. Pantke, N. Holle, A. Mogarkar, M. Straub, and V. Schulz. Multifrequency magnetic particle imaging enabled by a combined passive and active drive field feed-through compensation approach, Medical Physics, vol. 46, no. 9, pp. 4077–4086, Jul. 2019.
[5] H. Radermacher, V. Schulz, and F. Schrank, “Vorrichtung fuer die Anregung einer magnetischen oder zumindest magnetisierbaren Probe und Verfahren zur Durchgriffsreduktion,” pat., German Patent Application 102023124503.

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