International Journal on Magnetic Particle Imaging IJMPI
Vol. 11 No. 1 Suppl 1 (2025): Int J Mag Part Imag
https://doi.org/10.18416/IJMPI.2025.2503020

Proceedings Articles

Comparison of receive inserts for non-human primate fMPI in a human brain scanner

Main Article Content

Frauke H. Niebel (1) Fraunhofer IMTE, Fraunhofer Research Institution for Individualized and Cell-Based Medical Engineering, Lübeck, Germany; 2) Institute of Medical Engineering, University of Lübeck, Lübeck, Germany; 3) Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, USA), Alex C. Barksdale (1) Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, USA; 2) Massachusetts Institute of Technology, Cambridge, MA, USA), Monika Sliwiak (Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, USA), Eli Mattingly (1) Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, USA; 2) Harvard-MIT Division of Health Sciences & Technology, Cambridge, MA, USA; 3) Massachusetts Institute of Technology, Cambridge, MA, USA), Jorge Chacon-Caldera (1) Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, USA; 2) Harvard Medical School, Boston, MA, USA), Lawrence L. Wald (1) Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, USA; 2) Harvard-MIT Division of Health Sciences & Technology, Cambridge, MA, USA; 3) Harvard Medical School, Boston, MA, USA)

Copyright (c) 2025 Frauke H. Niebel, Alex C. Barksdale, Monika Sliwiak, Eli Mattingly, Jorge Chacon-Caldera, Lawrence L. Wald

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Abstract

The receive coil geometry significantly influences MPI detection sensitivity, a primary distinguishing characteristic when competing with other tracer-based imaging methods.
Here, we compare four gradiometric receive inserts for non-human primate functional MPI to identify a coil geometry that maximizes sensitivity while accommodating the primate head. A cylindrical coil with a diameter of  14 cm provided the highest sensitivity while fitting the macaque. Smaller cross-section gradiometers offered better rejection of noise originating from the shift coil amplifiers.

Article Details

References

E. Mattingly, M. Sliwiak, J. Chacon-Caldera, A. Barksdale, F. Niebel,
E. Mason, and L. Wald. A human-scale magnetic particle imag
ing system for functional neuroimaging. International Journal on
Magnetic Particle Imaging IJMPI, 10(1 Suppl 1), 2024.

J. Chacon-Caldera, E. Mattingly, M. Sliwiak, A. C. Barksdale, F. H.
Niebel, and L. L. Wald. A receive insert for non-human primate
functional mpi (fmpi). International Journal on Magnetic Particle
Imaging IJMPI, 10(1 Suppl 1), 2024.

F. H. Niebel, J. Chacon-Caldera, E. Mattingly, A. C. Barksdale, M.
Sliwiak, and L. L. Wald. Analysis of noise sources in a human-scale
fmpi imager. International Journal on Magnetic Particle Imaging
IJMPI, 10(1 Suppl 1), 2024.

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