International Journal on Magnetic Particle Imaging IJMPI
Vol. 11 No. 1 Suppl 1 (2025): Int J Mag Part Imag
https://doi.org/10.18416/IJMPI.2025.2503026

Proceedings Articles

Simulation of Multi-Coil Single-Sided MPI System with Offset Field Spatial Encoding

Main Article Content

Qibin Wang (School of Life Science and Technology), Kaixiong Yang (School of Life Science and Technology, Xidian University & Engineering Research Center of Molecular and Neuro Imaging, Ministry of Education, Xi’an, Shaanxi 710126, China.), Linwen Hou (School of Life Science and Technology, Xidian University & Engineering Research Center of Molecular and Neuro Imaging, Ministry of Education, Xi’an, Shaanxi 710126, China.), Yihan Wang (School of Life Science and Technology, Xidian University & Engineering Research Center of Molecular and Neuro Imaging, Ministry of Education, Xi’an, Shaanxi 710126, China.), Franziska Schrank (Institute for Experimental Molecular Imaging, RWTH Aachen University, Aachen, Germany; Institute of Imaging and Computer Vision, RWTH Aachen University, 52074 Aachen, Germany.), Harald Radermacher (Institute for Experimental Molecular Imaging, RWTH Aachen University, Aachen, Germany; Institute of Imaging and Computer Vision, RWTH Aachen University, 52074 Aachen, Germany.), Volkmar Schulz (Institute for Experimental Molecular Imaging, RWTH Aachen University, Aachen, Germany; Institute of Imaging and Computer Vision, RWTH Aachen University, 52074 Aachen, Germany; Fraunhofer Institute for Digital Medicine MEVIS, Aachen, Germany.), Shouping Zhu (School of Life Science and Technology, Xidian University & Engineering Research Center of Molecular and Neuro Imaging, Ministry of Education, Xi’an, Shaanxi 710126, China.)

Copyright (c) 2025 Qibin Wang, Kaixiong Yang, Linwen Hou, Yihan Wang, Franziska Schrank, Harald Radermacher, Volkmar Schulz, Shouping Zhu

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Abstract

Single-sided Magnetic particle imaging (MPI) systems have great potential for clinical applications because it concentrates all hardware on one side, allowing for an unrestricted imaging volume. However, the non-uniform magnetic field distribution in single-sided MPI devices poses challenges for generating high gradient selection fields. To address this, we developed a new offset field spatial encoding technique that combines amplitude modulation technology within a multi-coil structure, enabling 3D imaging without the need for classical selection fields and mechanical movement scanning. In simulation experiments, we validated the feasibility of this design, and the results indicate that the single-sided MPI device based on multi-coil amplitude modulation technology has the potential to achieve high spatial resolution and high temporal resolution.

Article Details

References

[1] Gräfe K, von Gladiss A, Bringout G, et al. 2D images recorded with a single-sided magnetic particle imaging scanner. IEEE transactions on medical imaging, 2015, 35(4): 1056-1065.
[2] McDonough C, Chrisekos J, Tonyushkin A. Tomographic Magnetic Particle Imaging with a Single-Sided Field-Free Line Scanner. IEEE Transactions on Biomedical Engineering, 2024.
[3] Q. Wang et al., “Simulation of a single-sided MPI handheld device with offset magnetic field for spatial encoding,” IJMPI, vol. 10, no. 1, Mar. 2024.
[4] P. C. Hansen and D. P. O’Leary, “The Use of the L-Curve in the Regularization of Discrete Ill-Posed Problems,” SIAM Journal on Scientific Computing, vol. 14, no. 6, pp. 1487–1503, Dec. 1993.

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