International Journal on Magnetic Particle Imaging IJMPI
Vol. 11 No. 1 Suppl 1 (2025): Int J Mag Part Imag
https://doi.org/10.18416/IJMPI.2025.2503016
Single-harmonic-based narrowband MPI: Effect of different harmonics
Main Article Content
Copyright (c) 2025 Jing Zhong, Chunhao Yin, Shijie Sun, Lijun Xu

This work is licensed under a Creative Commons Attribution 4.0 International License.
Abstract
Single-harmonic-based narrowband magnetic particle imaging (MPI) is one of the most promising approaches, which only measures only a single harmonic to visualize the spatial distribution of superparamagnetic iron oxide nanoparticles (SPIONs). In this paper, we investigate the effect of different harmonics, e.g. the 3rd, the 5th and the 7th harmonic, on the spatial resolution of single-harmonic-based narrowband MPI. The point spread functions of different harmonics at an excitation magnetic field of 4 mT and 10 kHz are simulated and evaluated by comparing the full width at half maximum (FWHM). Different harmonics of the 3rd, the 5th, and the 7th harmonics are used to reconstruct MPI images to investigate their effects on the spatial resolution. Simulation results indicates that with increasing harmonic order, the FWHM get narrower and the spatial resolution gets improved.