International Journal on Magnetic Particle Imaging IJMPI
Vol. 11 No. 1 Suppl 1 (2025): Int J Mag Part Imag
https://doi.org/10.18416/IJMPI.2025.2503037

Proceedings Articles

Preclinical Open-Sided Magnetic Particle Imaging Scanner

Main Article Content

Sefa Karaca (ASELSAN Research Center, ASELSAN A.Ş.), Damla Alptekin Soydan (1) Aselsan A.Ş.), Şirin Yazar Buran (1) Aselsan A.Ş.), Ali Alper Özaslan (1) Aselsan A.Ş.), Can Barış Top (1) Aselsan A.Ş.)

Abstract

Preclinical magnetic particle imaging (MPI) plays a crucial role in advancing biomedical research through in vivo studies and helps with the translation into clinical systems. Our previously developed open-sided MPI system was capable of electronic rotation and translation of the field-free line (FFL) in three dimensions. However, the field of view (FOV) was limited to 34 x 18 x 12 mm3 due to restrictions of the drive and receive coils. Here we introduce, a preclinical MPI system with a FOV of 100 x 50 x 25 mm3, which is suitable for tumor imaging in small mice. We present the imaging system design and 2D imaging results of the phantom obtained using the developed scanner.

Article Details

References

[1] Z.W. Tay, P. Chandrasekharan, B.D. Fellows, I. R. Arrizabalaga, E. Yu, M. Olivo, and S. M. Conolly.Magnetic particle imaging: An emerging modality with prospects in diagnosis, targeting and therapy of cancer. Cancers, 13(21), 2021, doi:10.3390/cancers13215285.
[2] C. B. Top and A. Güngör. Tomographic field free line magnetic particle imaging with an open-sided scanner configuration. IEEE Transactions on Medical Imaging, 39(12):4164–4173, 2020, doi:10.1109/TMI.2020.3014197.
[3] A. Güngör, B. Askin, D. A. Soydan, E. U. Saritas, C. B. Top, and T.Çukur. TranSMS: Transformers for super-resolution calibration in magnetic particle imaging. IEEE Transactions on Medical Imaging, 41(12):3562–3574, 2022, doi:10.1109/TMI.2022.3189693.
[4] A. Güngör, B. Askin, D. A. Soydan, C. B. Top, E. U. Saritas, and T. Çukur. DEQ-MPI: A deep equilibrium reconstruction with learned consistency for magnetic particle imaging. IEEE Transactions on Medical Imaging, 43(1):321–334, 2024, doi:10.1109/TMI.2023.3300704.

Most read articles by the same author(s)

1 2 > >>