International Journal on Magnetic Particle Imaging IJMPI
Vol. 11 No. 1 Suppl 1 (2025): Int J Mag Part Imag
https://doi.org/10.18416/IJMPI.2025.2503063

Proceedings Articles

A smart combination: A study on viscosity influences on SMART RHESINS using COMPASS

Main Article Content

Johanna Günther (Universität Würzburg Experimentelle Physik 5), Julia Feye (1) Faculty of Engineering, Baden-Württemberg Cooperative State University Karlsruhe, Germany; 2) Insititute of Inorganic Chemistry, Karlsruhe Institute of Technology (KIT), Germany.), Thomas Kampf (1)Department of Experimental Physics 5 (Biophysics), Julius-Maximilians-University Würzburg, Germany; 2)Department of Diagnostic and Interventional Neuroradiology, University Hospital Würzburg, Germany.), Martin Andreas Rückert (Department of Experimental Physics 5 (Biophysics), Julius-Maximilians-University Würzburg, Germany.), Teresa Reichl (Department of Experimental Physics 5 (Biophysics), Julius-Maximilians-University Würzburg, Germany.), Rainer Tietze (Department of Otorhinolaryngology, Head and Neck Surgery, Section of Experimental Oncology and Nanomedicine (SEON), Else Kröner-Fresenius-Stiftung-Professorship, University Hospital Erlangen, Germany.), Esther Rösch (1) Faculty of Engineering, Baden-Württemberg Cooperative State University Karlsruhe, Germany; 2) Insititute of Inorganic Chemistry, Karlsruhe Institute of Technology (KIT), Germany.), Peter W. Roesky (Insititute of Inorganic Chemistry, Karlsruhe Institute of Technology (KIT), Germany.), Patrick Vogel (Department of Experimental Physics 5 (Biophysics), Julius-Maximilians-University Würzburg, Germany.), Volker Christian Behr (Department of Experimental Physics 5 (Biophysics), Julius-Maximilians-University Würzburg, Germany.)

Abstract

To enable reliable quantification of magnetic nanoparticles, new methods to prevent interactions of particles with their physiological environment are necessary. An innovative approach are SMART RHESINs, where conventional nanoparticles are encapsulated in hollow nanospheres. Here, a detailed study on Perimag® based SMART RHESINs has been performed utilizing critical offset magnetic particle spectroscopy (COMPASS) to show that the influence of the surrounding medium, which was varied in viscosity, on the particle system can be suppressed using SMART RHESINs.

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