International Journal on Magnetic Particle Imaging IJMPI
Vol. 11 No. 1 Suppl 1 (2025): Int J Mag Part Imag
Design and Implementation of a Novel Surface Excitation Coil for a Single-Sided Field Free Line MPI Scanner
Main Article Content
Copyright (c) 2025 Chris McDonough, John Chrisekos, Alexey Tonyushkin

This work is licensed under a Creative Commons Attribution 4.0 International License.
Abstract
In MPI, designing whole-body hardware for clinically relevant imaging remains non-trivial. Single-sided scanner designs, which confine hardware to one side of the imaging volume, offer an open imaging volume but suffer from inhomogeneous magnetic fields, resulting in decreased sensitivity and spatial resolution away from the scanner. Here, we redesigned our single-sided field-free line scanner by implementing a novel organ-specific surface excitation coil. This upgrade highlights the potential of the scanner to significantly improve sensitivity and image quality in single-sided MPI applications.
Article Details
References
Boberg, F. Griese, M. Möddel, P. Ludewig, D. van de Ven, O. M. We-
ber, O. Woywode, B. Gleich, and T. Knopp. Human-sized magnetic
particle imaging for brain applications. Nature Communications,
10(1), 2019, doi:10.1038/s41467-019-09704-x.
[2] P. Vogel, M. A. Rückert, C. Greiner, J. Günther, T. Reichl, T. Kampf,
T. A. Bley, V. C. Behr, and S. Herz. Impi: Portable human-sized mag-
netic particle imaging scanner for real-time endovascular interven-
tions. Scientific Reports, 13:10472, 1 2023, doi:10.1038/s41598-023-
37351-2.
[3] C. McDonough, J. Chrisekos, and A. Tonyushkin. Tomographic
magnetic particle imaging with a single-sided field-free line scan-
ner. IEEE Transactions on Biomedical Engineering, pp. 1–12, 2024,
doi:10.1109/TBME.2024.3427665.
[4] T. F. Sattel, T. Knopp, S. Biederer, B. Gleich, J. Weizenecker, J. Borg-
ert, and T. M. Buzug. Single-sided device for magnetic particle
imaging. Journal of Physics D: Applied Physics, 42(2):022001, 2009,
doi:10.1088/0022-3727/42/2/022001.
[5] K. Gräfe, A. von Gladiss, G. Bringout, M. Ahlborg, and T. M. Buzug.
2D Images Recorded With a Single-Sided Magnetic Particle Imaging
Scanner. IEEE Transactions on Medical Imaging, 35(4):1056–1065,
2016, doi:10.1109/TMI.2015.2507187.
[6] A. Tonyushkin. Single-Sided Field-Free Line Generator
Magnet for Multi-Dimensional Magnetic Particle Imag-
ing. IEEE Transactions on Magnetics, 53(9):5300506, 2017,
doi:10.1109/TMAG.2017.2718485.
[7] C. McDonough, J. Pagan, and A. Tonyushkin. Implementation of the
surface gradiometer receive coils for the improved detection limit
and sensitivity in the single-sided mpi scanner. Physics in Medicine
& Biology, 67(24):245009, 2022, doi:10.1088/1361-6560/aca5ec.
[8] C. Chinchilla, C. McDonough, A. Negash, J. Pagan, and A.
Tonyushkin. Simulation studies of image reconstruction for field
free line single-sided magnetic particle imaging scanner. Interna-
tional journal on magnetic particle imaging, 7(1):2104001, 2021.