International Journal on Magnetic Particle Imaging IJMPI
Vol. 8 No. 1 Suppl 1 (2022): Int J Mag Part Imag
Imaging of the lumen of intracranial flow diverter stents with MPI
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Copyright (c) 2022 Moriz Herzberg, Martin Rückert, Franziska Dorn, Thomas Kampf, Thorsten Bley, Volker Behr, Stefan Herz, Patrick Vogel
This work is licensed under a Creative Commons Attribution 4.0 International License.
Abstract
Flow diverter (FD) for the endovascular treatment of intracranial aneurysms are an innovative new stent design. These nitinol stents modulate the turbulent inflow into an aneurysm, offering the potential of occlusion through thrombosis. After treatment follow-up imaging is necessary. Digital subtraction angiography is the gold-standard in follow-up of flow-diverters, yet its invasiveness with an 1% complication rate and patient exposure to ionizing radiation limit its application. The metallic stent material causes artifacts in computed tomography and magnetic resonance imaging compromising clinical interpretation. Magnetic particle imaging (MPI) is a fast and sensitive tomographic imaging modality that uses magnetic fields to visualize superparamagnetic iron-oxide nanoparticles (SPIOs). Inherent advantages of MPI are the background- and radiation-free visualization of tracer material. Thus, magnetic particle imaging (MPI) may be beneficial for patients with FD treated aneurysms. The aim of this work was to illustrate the feasibility of MPI visualizing the stent lumen of flow diverters in a phantom study
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References
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[3] T. Ingall, K. Asplund, M. Mähönen, R. Bonita, A multinational comparison of subarachnoid hemorrhage epidemiology in the WHO MONICA stroke study, Stroke 31 (2000) 1054–1061.
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[9] Y.H. Ding, T. Tieu, D.F. Kallmes, Experimental testing of a new generation of flow diverters in sidewall aneurysms in rabbits, AJNR. American journal of neuroradiology 36 (2015) 732–736.
[10] S. Herz, P. Vogel, P. Dietrich, T. Kampf, M.A. Rückert, R. Kickuth et al., Magnetic Particle Imaging Guided Real-Time Percutaneous Transluminal Angioplasty in a Phantom Model, Cardiovascular and interventional radiology 41 (2018) 1100–1105.
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