International Journal on Magnetic Particle Imaging IJMPI
Vol. 9 No. 1 Suppl 1 (2023): Int J Mag Part Imag
https://doi.org/10.18416/IJMPI.2023.2303018
Core size analysis of magnetic nanoparticles using frequency mixing magnetic detection with a permanent magnet as an offset source
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This work is licensed under a Creative Commons Attribution 4.0 International License.
Abstract
Frequency mixing magnetic detection (FMMD) has been widely used in magnetic immunoassay measurement techniques. It can also be used to characterize and distinguish different magnetic nanoparticle (MNP) types according to their magnetic cores size. In a previous work, a method for resolving ambiguities in determination of the core size distribution was utilized involving measurement of total iron mass. Recently, a new FMMD measurement head was developed in which a pair of permanent ring magnets are used to generate the static offset magnetic field. Here, we show that this new measurement head can be applied for determining the core size distribution of MNP, and compare the results with the outcomes of our conventional electromagnet offset module FMMD.
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