Development of a Magnetically Responsive Polydimethylsiloxane Composite with Optimized SPION Distribution for Coating of Medical Devices

Helena Seso; Ankit Malhotra; Kerstin Lüdtke-Buzug

doi:10.18416/IJMPI.2025.2503060

International Journal on Magnetic Particle Imaging IJMPI
Vol. 11 No. 1 Suppl 1 (2025): Int J Mag Part Imag
https://doi.org/10.18416/IJMPI.2025.2503060

Proceedings Articles

Development of a Magnetically Responsive Polydimethylsiloxane Composite with Optimized SPION Distribution for Coating of Medical Devices

Helena Seso (Institute of Medical Engineering, University of Lübeck), Ankit Malhotra (Fraunhofer Research Institution for Individualized and Cell-Based Medical Engineering IMTE, Lübeck, Germany), Kerstin Lüdtke-Buzug (Institute of Medical Engineering, University of Lübeck and Fraunhofer Research Institution for Individualized and Cell-Based Medical Engineering IMTE, Lübeck, Germany)

This work is licensed under a Creative Commons Attribution 4.0 International License.

Abstract

This study introduces the development of an innovative polydimethylsiloxane (PDMS) composite enhanced with superparamagnetic iron oxide nanoparticles (SPIONs), specifically engineered as a polymer coating for medical devices and as a functional material for Magnetic Particle Imaging (MPI) in diagnostic applications. To achieve uniform spatial dispersion of nanoparticles within the PDMS matrix, ultrasonic treatment was employed, effectively enhancing the homogeneity of SPION distribution throughout the polymer structure. The results demonstrate significant promise for this superparamagnetic composite, offering new avenues in the advancement of polymer-based materials for medical imaging and device technology.

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